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for 'project feed 1010'

  • Project Feed 1010 – Sustainable Agriculture

    ISB is actively working on Project Feed 1010, a demonstration project and laying the experimental, computational, cloud-computing and social networking infrastructure for a first-of-its-kind network of farmers, scientists and educators to crowdsource sustainable agriculture research and education.

  • 100K Wellness Project

    The Institute for Systems Biology (ISB) pioneered and has been recognized as the world leader in the systems approach to studying biology for the past 15 years. Guided by the vision of Dr. Lee Hood, ISB’s president and co-founder, ISB has also pioneered the concept of P4 Medicine (personalized, predictive, preventive, and participatory). This combination of a systems biology approach with P4 Medicine led to ISB launching in 2014, and completing in 2015, a pilot study called the Hundred Person Wellness Project (HPWP).

  • Pan-Cancer Project

    The Cancer Genome Atlas research network has launched the Pan-Cancer project to analyze multiple tumor types together to find common events across different tumors. The availability of large cohorts and multiple different types of data at the DNA, RNA, and protein levels has made the Pan-Cancer project possible.

  • ISB’s PeptideAtlas Helps Advance the Study of Proteins

    The Human Proteome Project expands on the work of the Human Genome Project.
    ISB is a leader in proteomics and developed PeptideAtlas, a project that has cataloged the proteins observed in thousands of proteomics experiments as an open resource for researchers everywhere.
    In a new report, ISB researchers show that PeptideAtlas now contains proteins from about 62 percent of human genes thought to encode proteins.

  • Wilke Cohen Lyme Disease Project

    ISB researchers have put their efforts into looking at Lyme disease and the bacteria, Borrelia burgdorferi, that causes the disease, through the lens of systems biology, and utilizing approaches pioneered at ISB to gather, synthesize and interpret large and complex datasets.

  • P100 Cover

    Pioneer 100 Study Show Data, Coaching Can Optimize Individual Wellness

    Results from the Pioneer 100 Wellness Project, a nine-month study of 108 individuals, demonstrated that combining personal, dense, dynamic data clouds with tailored behavioral coaching can optimize wellness for individuals. These data clouds also can identify early transitions into disease states and facilitate the reversal of some disease states back to wellness.

  • ‘Demystifying Disease, Democratizing Health Care’

    In Science Translational Medicine, Dr. Lee Hood and Dr. Nathan Price, of Institute for Systems Biology, deliver an editorial stating the vision of the 100K Wellness Project. The project will track health-related data types for 100K individuals longitudinally over the course of 20-30 or more years.Dr. Lee Hood and Dr. Nathan Price, of Institute for Systems Biology, deliver an editorial stating the vision of the 100K Wellness Project. The project will track health-related data types for 100K individuals longitudinally over the course of 20-30 or more years.

  • Placenta and Preterm Birth

    ISB is using systems biology to map molecular network dynamics in normal pregnancy, as well as study changes that occur in pregnancies with complications such as preterm birth. By using a systems approach, we hope to gain a more comprehensive understanding of pathological changes that occur in pregnancy, and identify women most at risk of developing pregnancy complications.

  • Identifying Four New Subtypes of Gastric Cancer That May Lead to New Targeted Treatments

    Gastric cancer has a high mortality rate, but current classification systems haven’t been effective in helping to identify subtypes relevant for treatment of the disease.
    TCGA researchers have integrated molecular data from 295 stomach tumors and have discovered four subtypes of gastric cancer.
    Stratification of patients into these four subtypes paves the way for the development of new personalized therapies.

  • Warhol style Plasmodium

    Identification of the proteins in Plasmodium vivax provide new targets for a malaria vaccine

    Scientists from ISB and the Center for Infectious Disease Research led an international collaboration to identify proteins in the malaria parasite Plasmodium vivax. P. vivax and P. falciparum cause the majority of malaria cases, but P. vivax is far less-studied, in part because it cannot be grown in the lab. The research aims to provide new targets for a malaria vaccine.

  • Stress Test Predicts How Diatoms Will React to Ocean Acidification

    The foundation of many marine food webs in which corals, fish and whales depend on are microscopic photosynthetic algae called diatoms. ISB scientists have developed a stress test to quantify and predict how ocean acidification would impact the resilience of diatoms in the future.

  • Novel clustering algorithm identifies functional mutations in cancer genes

    In a study published in PLoS Computational Biology, researchers at Institute for Systems Biology (ISB) have developed a multiscale mutation clustering algorithm (M2C) that identifies variable length regions with high mutation density in cancer genes.